Large Language Models

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Friday, 11 September 2026

Sakana AI Launches Fugu Max and Fugu Ultra v2 for Cheaper, Stronger Multi-Agent Orchestration

MarkTechPost 1 month ago 27 ● 2 sources

Sakana AI launched Fugu Max and Fugu Ultra v2, two multi-agent orchestration models in its Sakana Fugu family available via a hosted API. Fugu Max is priced at $2 per 1M input tokens and $6 per 1M output tokens. The models route work across multiple underlying models to optimize either best output per dollar or highest capability on hard multi-step tasks, without providing open weights.

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AI Infrastructure Large Language Models Agent Orchestration Sakana AI

SimpleDesign: A Joint Model for Protein Sequence and Structure Codesign

Apple Machine Learning Research 1 month ago 17

SimpleDesign introduces an end-to-end protein design model that jointly generates amino-acid sequences and 3D structures instead of using a two-stage latent-space pipeline. SimpleDesign is trained on over 2M sequence–structure pairs. As a result, it uses a single-stage objective with sequence cross-entropy and structure regression while employing Transformer-based multimodal backbones, achieving competitive performance on co-design and unconditional generation benchmarks.

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Large Language Models Model Training Scientific Research Multimodal Models

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