Researchers used AlphaFold to identify regions of gene-editing proteins that cause off-target DNA edits, then modified those regions to reduce errors. The modified proteins showed improvements in specificity compared to original versions. This approach could make gene-editing therapies safer by reducing the risk of unintended genetic changes in treated cells.
The Trump administration announced $5 billion in Genesis Mission grants for AI-driven science projects and outlined a science policy prioritizing artificial intelligence, robotics, and nuclear energy while downplaying life sciences. The funding will support hundreds of AI projects through grants that the White House compared to the Manhattan Project in scale and urgency. This marks a significant shift in U.S. scientific priorities toward AI and away from traditional life sciences research.
Allen Institute (AI2)·1 month ago·
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● 74 sources
Ai2 argues that open-weight AI models with publicly available training data, code, and evaluation details are essential for scientific progress and public understanding of AI systems. The organization has released fully transparent models like Olmo that enable independent researchers at universities and nonprofits to investigate model behavior, study bias, and test safety claims without relying on corporate assurances. Open science infrastructure maintains broader participation in AI research and prevents technical direction from concentrating solely within large companies.
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