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CuspAI lands $450m round to accelerate AI materials discovery

Sifted Covered by 2 sources

CuspAI just raised $450m to hunt for materials that don't exist yet. That's a $2.6bn valuation, four times higher than a year ago.

Based on reporting by Sifted — read the original for the full story.

Summary, retelling and take written by AI under human oversight; images are AI-generated illustrations. How we work · Report an error

Cambridge-based CuspAI has closed a $450m Series B, pushing its valuation to $2.6bn — more than four times what it was worth after its $100m raise last September. Kleiner Perkins and NEA led the round, with Jeff Bezos's family office among the backers. That's a serious vote of confidence for a company barely 18 months old, and it confirms what the Financial Times reported earlier this year about talks at this exact valuation.

The company, founded in 2024 by Chad Edwards and Max Welling, is trying to use AI to design materials that don't currently exist — things needed for semiconductors, batteries, and manufacturing that chemistry alone hasn't produced yet. Edwards frames it starkly: without faster progress here, he says, the next five decades of industrial advancement gets bottlenecked by a lack of new materials. It's a big claim, but it's the pitch that's apparently persuaded investors to write some very large checks.

Alongside the funding, CuspAI launched something called the AI Materials Foundry, essentially a consortium stitching together compute, lab access, proprietary data, and scientific know-how. More than 45 organizations signed on as founding members, and the list is notable: Nvidia is supplying compute, Meta's Fundamental AI Research team is involved, and so are Samsung, Hyundai, Hitachi High-Tech, and Merck. That's a mix of chip makers, carmakers, and pharma companies all betting on the same discovery pipeline. CuspAI's own platform, called MIRA, is meant to run the whole process — from proposing candidate materials to simulating them and eventually validating them in real labs.

The money will fund expansion into the US, Europe, and Asia, according to the company. CuspAI already topped Sifted's AI 100 list last year for European startups under $1bn — a ranking it has now blown past. Its board reads like a who's-who of AI research, with Yann LeCun and Geoffrey Hinton both involved, alongside existing backers like Lightspeed, Northzone, and Temasek.

My take — AI-written commentary, not fact-checked reporting

A $2.6bn valuation for a company that hasn't shipped a commercial material yet tells you where the money is chasing next — AI-for-science is the new frontier after the LLM gold rush cooled off. I'm generally skeptical of these eye-watering pre-revenue valuations, but materials discovery is one of the few domains where AI's pattern-matching could genuinely compress decades of lab work into years, so this one might actually earn its hype.

Read more about this at: Sifted

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