Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub

Latent Space · 4 days ago · 39

Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido discussed why AlphaFold’s protein-structure success hasn’t solved protein folding or broader biology modeling. They pointed to a goal of 10x–100x acceleration in drug discovery as part of what future AI-driven biology would need to deliver. The focus shifts from scaling compute and data alone toward finding the right biological scaling laws, improving data and inductive biases, and modeling dynamics and whole-cell systems with more trustworthy uncertainty handling.