Uncovering repurposed medicines to fight liver fibrosis

Google DeepMind · 2 months ago

Researchers at Stanford University used an AI tool called Co-Scientist to identify existing medicines that could treat liver fibrosis, a scarring condition that kills over 1.4 million people annually. When tested against human liver cells, two of three AI-selected drug candidates blocked fibrosis progression, while the cancer drug vorinostat blocked 91% of a damage response driving liver scarring. The findings suggest that drugs altering gene activity patterns warrant clinical investigation as potential treatments for the condition.