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Drug Discovery

56 summarised stories about Drug Discovery, each linking back to the original source. Browse all topics →

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Wednesday, 17 June 2026

A near-autonomous AI chemist improves a challenging reaction in medicinal chemistry

OpenAI 3 months ago 31

OpenAI and Molecule.one deployed an AI system based on GPT-5.4 to optimize a difficult chemical reaction used in drug manufacturing. The AI chemist improved yield or efficiency metrics for a key medicinal chemistry reaction, though specific performance gains are not quantified in the available details. This demonstrates potential for AI systems to accelerate chemical synthesis optimization without constant human supervision.

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