TLDRocket
Sign in

Healthcare

45 summarised stories about Healthcare, each linking back to the original source. Browse all topics →

Tuesday, 25 November 2025

AlphaFold: Five years of impact

Google DeepMind 7 months ago

AlphaFold, an AI system for predicting protein structures, has been used by over 3 million researchers across more than 190 countries since its 2021 public release. The system has generated predictions for more than 200 million protein structures and been cited in over 35,000 papers, with researchers using it showing a 40% increase in submitting novel experimental structures. The tool has enabled practical applications ranging from developing healthier honeybee populations to revealing the structure of a key heart disease protein, and spawned related AI models for genetic mutation assessment and protein design.

Revealing a key protein behind heart disease

Google DeepMind 7 months ago

Scientists at the University of Missouri used AlphaFold and cryo-electron microscopy to map the structure of apoB100, the protein that forms the molecular scaffold of low-density lipoprotein (LDL) or "bad cholesterol." Researchers have sought this protein's structure for 50 years due to its size and complexity. The discovery could enable development of more targeted therapies for atherosclerotic cardiovascular disease, the world's leading cause of death.